Cyanobacteria utilize an elegant photoprotection mechanism mediated by the photoactive Orange Carotenoid Protein (OCP), which upon binding dissipates excess energy from light-harvesting complexes, phycobilisomes. The OCP activity is efficiently regulated by its partner, the Fluorescence Recovery Protein (FRP). FRP accelerates OCP conversion to the resting state, thus counteracting the OCP-mediated photoprotection. Behind the deceptive simplicity of such regulation is hidden a multistep process involving dramatic conformational rearrangements in OCP and FRP, the details of which became clearer only a decade after the FRP discovery. Yet many questions regarding the functioning of FRP have remained controversial. In this review, we summarize the current knowledge and understanding of the FRP role in cyanobacterial photoprotection as well as its evolutionary history that presumably lies far beyond cyanobacteria.

中文翻译：

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荧光恢复蛋白：蓝细菌中光保护的功能强大但尚未开发的调节剂

蓝细菌利用由光敏性橙色类胡萝卜素蛋白（OCP）介导的优雅的光保护机制，该机制在结合时会耗散来自采光复合物藻胆体的多余能量。OCP活性受到其伙伴荧光恢复蛋白（FRP）的有效调节。FRP加速了OCP转换为静止状态，从而抵消了OCP介导的光保护作用。这种监管方法的欺骗性简单性背后隐藏着一个多步骤的过程，该过程涉及OCP和FRP中剧烈的构象重排，其详细信息在FRP发现十年后才变得更加清晰。关于玻璃钢功能的许多问题仍存在争议。在这篇评论中