Abstract

Purpose

Pelvic incidence (PI) is unique to each individual and does not change throughout life. High PI is related to lumbar spondylolisthesis, but associations of PI with lumbar osteophyte formation and disc degeneration are unclear. The objective was to evaluate relationships of PI with lumbar osteophyte formation and disc degeneration, as well as spinal sagittal alignment and geriatric diseases, in middle-aged and elderly people.

Methods

A total of 1002 volunteers (male: 434, female: 568, average age: 63.5) were prospectively examined for lumbar osteophyte formation (Nathan class ≥ 2) and disc degeneration (disc score ≥ 3). High (PI > 51, n = 501) and low (PI ≤ 51, n = 501) PI groups were defined. Clinical factors, frailty, sarcopenia, and physical quality of life (QOL) were compared between these groups, and risk factors for lumbar osteophyte formation and disc degeneration were identified in multivariate logistic regression analysis.

Results

Physical QOL was poorer in people with lumbar osteophyte formation (54.8%) and disc degeneration (33.6%). Age, male gender, spinal parameters including PI, bone mineral density, back muscle strength, and gait ability differed significantly between the groups, whereas frailty and sarcopenia were not significantly different. Low PI, low lumbar lordosis, elder age, male gender, high BMI, and weak back muscle strength were significant risk factors for lumbar osteophyte formation and disc degeneration.

Conclusions

Low PI was identified as a risk factor for lumbar osteophyte formation and disc degeneration, both of which reduce physical QOL in middle-aged and elderly people.

Graphic abstract

These slides can be retrieved under Electronic Supplementary Material.

中文翻译：

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在预期的横断面队列研究中，骨盆发生率对中老年人腰椎骨赘形成和椎间盘退变的影响。

摘要

目的

骨盆发生率（PI）对于每个人来说都是唯一的，并且一生都不会改变。高PI与腰椎滑脱有关，但PI与腰椎骨赘形成和椎间盘退变的相关性尚不清楚。目的是评估中老年人中PI与腰椎骨赘形成和椎间盘退变以及脊髓矢状位和老年性疾病的关系。

方法

前瞻性检查了总共1002名志愿者（男：434名，女：568名，平均年龄：63.5岁）的腰椎骨赘形成（内森≥2级）和椎间盘退变（椎间盘评分≥3）。定义了高（PI> 51，n  = 501）和低（PI≤51，n  = 501）PI组。比较了这两组患者的临床因素，虚弱，肌肉减少症和生活质量（QOL），并通过多因素logistic回归分析确定了腰椎骨赘形成和椎间盘退变的危险因素。

结果

腰椎骨赘形成（54.8％）和椎间盘退变（33.6％）的人的身体素质较差。年龄，男性，脊柱参数（包括PI），骨矿物质密度，背部肌肉力量和步态能力在两组之间有显着差异，而虚弱和肌肉减少症则无显着差异。PI低，腰椎前凸低，年龄大，男性，BMI高和后肌力量弱是腰椎骨赘形成和椎间盘退变的重要危险因素。

结论

低PI被认为是腰椎骨赘形成和椎间盘退变的危险因素，两者均会降低中老年人的身体QOL。

图形摘要

这些幻灯片可以在电子补充材料下找到。