The current study compared optical quality before and after implantation of a posterior chamber phakic intraocular lens with a central hole [V4c implantable collamer lens (ICL)] under bright and dark lighting conditions by means of the Optical Quality Analysis System™ (OQAS; Visiometrics, Terrassa, Spain). This prospective study involved 91 eyes of 46 consecutive high myopia patients (15 males and 31 females, average spherical equivalent − 10.50 ± 0.33D) undergoing implantation of a V4c ICL. The modulation transfer function (MTF) cutoff frequency, Strehl ratio, objective scattering index (OSI), and predicted visual acuities (PVAs; 100, 20, and 9%), under different lighting conditions, were measured before and 1 week, 1 month, and 3 months after surgery. All optical parameters showed significant improvements, at all time points, under dark condition after surgery. We observed no significant changes in PVA 9% at 1 week (mean value 0.539, P = 0.12) or 1 month after surgery (mean value 0.573, P = 0.08) under bright condition; but all other postoperative parameters improved significantly. Comparing the two lighting conditions, the OSI decreased more under dark conditions at 1 week (P = 0.02), 1 month (P = 0.004), and 3 months (P = 0.002), but there was no significant difference in any other parameter. In addition, patients were divided into super high myopia (group S, spherical equivalent greater than − 10 D) and high myopia (group H, spherical equivalent from − 6 D to − 10 D), the group S improved significantly more than group H in all parameters, under both bright and dark conditions. V4c ICL implantation improved optical quality under both bright and dark lighting conditions, and had a better ability to reduce the extent of scattering in the dark. Furthermore, group S achieved greater improvement in visual quality, which should be considered by physicians before surgery.

中文翻译：

---

在不同照明条件下后房角膜植入有中心孔的人工晶状体（V4c植入式Collamer晶状体）后的光学质量

当前的研究通过光学质量分析系统（OQAS; Visiometrics）比较了在明亮和黑暗的照明条件下，在有中央孔的后房有晶状体人工晶状体植入前后的光学质量[V4c可植入的聚光透镜（ICL）]西班牙Terrassa）。这项前瞻性研究涉及接受V4c ICL植入的46例连续高度近视患者（男性15例，女性31例，平均球当量-10.50±0.33D）的91眼。在不同的光照条件下，在1周，1个月之前和1周内测量了调制传递函数（MTF）的截止频率，斯特列尔比，客观散射指数（OSI）和预测的视敏度（PVA； 100％，20％和9％） ，以及术后3个月。在所有时间点，所有光学参数均显示出显着改善，手术后在黑暗条件下。在明亮的条件下，术后1周（平均值0.539，P = 0.12）或术后1个月（平均值0.573，P = 0.08），PVA 9％均无明显变化；但所有其他术后参数均明显改善。比较这两种光照条件，在黑暗条件下1周（P = 0.02），1个月（P = 0.004）和3个月（P = 0.002）时，OSI下降更多，但其他任何参数均无显着差异。此外，将患者分为超高度近视（S组，球体当量大于-10 D）和高度近视（H组，球体当量从-6 D到-10 D），S组比H组有明显改善在所有参数下，无论是在明暗条件下。V4c ICL植入改善了在明亮和黑暗照明条件下的光学质量，并具有减少黑暗中散射程度的更好能力。此外，S组在视觉质量上有更大的改善，医师应在手术前予以考虑。