The aim of this study was to evaluate the imaging quality and diagnostic performance of fast spin echo diffusion-weighted imaging with periodically rotated overlapping parallel lines with enhanced reconstruction (FSE-PROP-DWI) in distinguishing parotid pleomorphic adenoma (PMA) from Warthin tumor (WT). This retrospective study enrolled 44 parotid gland tumors from 34 patients, including 15 PMAs and 29 WTs with waived written informed consent. All participants underwent 1.5 T diffusion-weighted imaging including FSE-PROP-DWI and single-shot echo-planar diffusion-weighted imaging (SS-EP-DWI). After imaging resizing and registration among T2WI, FSE-PROP-DWI and SS-EP-DWI, imaging distortion was quantitatively analyzed by using the Dice coefficient. Signal-to-noise ratio and contrast-to-noise ratio were qualitatively evaluated. The mean apparent diffusion coefficient (ADC) of parotid gland tumors was calculated. Wilcoxon signed-rank test was used for paired comparison between FSE-PROP-DWI versus SS-EP-DWI. Mann-Whitney U test was used for independent group comparison between PMAs versus WTs. Diagnostic performance was evaluated by receiver operating characteristics curve analysis. P < 0.05 was considered statistically significant. The Dice coefficient was statistically significantly higher on FSE-PROP-DWI than SS-EP-DWI for both tumors (P < 0.005). Mean ADC was statistically significantly higher in PMAs than WTs on both FSE-PROP-DWI and SS-EP-DWI (P < 0.005). FSE-PROP-DWI and SS-EP-DWI successfully distinguished PMAs from WTs with an AUC of 0.880 and 0.945, respectively (P < 0.05). Sensitivity, specificity, positive predictive value, negative predictive value and accuracy in diagnosing PMAs were 100%, 69.0%, 62.5%, 100% and 79.5% for FSE-PROP-DWI, and 100%, 82.8%, 75%, 100% and 88.6% for SS-EP-DWI, respectively. FSE-PROP-DWI is useful to distinguish parotid PMAs from WTs with less distortion of tumors but lower AUC than SS-EP-DWI.

中文翻译：

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PROPELLER扩散加权MR成像的成像质量及其在区分腮腺Warthin肿瘤中的多形性腺瘤的诊断性能。

这项研究的目的是评估周期性旋转重叠平行线并增强重建（FSE-PROP-DWI）的快速自旋回波扩散加权成像的成像质量和诊断性能，以区分腮腺多形性腺瘤（PMA）与沃辛肿瘤（ WT）。这项回顾性研究招募了来自34例患者的44例腮腺肿瘤，其中包括15例PMA和29例WT，并获得了书面知情同意书。所有参与者均接受1.5 T扩散加权成像，包括FSE-PROP-DWI和单次回波平面扩散加权成像（SS-EP-DWI）。在调整图像大小并在T2WI，FSE-PROP-DWI和SS-EP-DWI中进行配准后，使用Dice系数对图像失真进行了定量分析。定性评估信噪比和对比噪声比。计算腮腺肿瘤的平均表观扩散系数（ADC）。Wilcoxon符号秩检验用于FSE-PROP-DWI与SS-EP-DWI之间的配对比较。Mann-Whitney U检验用于PMA与WT之间的独立组比较。通过接收器工作特性曲线分析评估诊断性能。P <0.05被认为具有统计学意义。在FSE-PROP-DWI上，两种肿瘤的Dice系数在统计学上均显着高于SS-EP-DWI（P <0.005）。在FSE-PROP-DWI和SS-EP-DWI上，PMA中的ADC均显着高于WT（P <0.005）。FSE-PROP-DWI和SS-EP-DWI成功将PMA与WT区别开，其AUC分别为0.880和0.945（P <0.05）。敏感性，特异性，阳性预测值，FSE-PROP-DWI诊断PMA的阴性预测值和准确性分别为100％，69.0％，62.5％，100％和79.5％，SS-EP-100％为82.8％，75％，100％和88.6％ DWI，分别。FSE-PROP-DWI有助于区分腮腺PMA与WT，而SS-EP-DWI的肿瘤变形较小，但AUC较低。