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PQQ-GDH - Structure, function and application in bioelectrochemistry.
Bioelectrochemistry ( IF 5 ) Pub Date : 2020-03-03 , DOI: 10.1016/j.bioelechem.2020.107496
Fred Lisdat 1
Affiliation  

This review summarizes the basic features of the PQQ-GDH enzyme as one of the sugar converting biocatalysts. Focus is on the membrane -bound and the soluble form. Furthermore, the main principles of enzymatic catalysis as well as studies on the physiological importance are reviewed. A short overview is given on developments in protein engineering. The major part, however, deals with the different fields of application in bioelectrochemistry. This includes approaches for enzyme-electrode communication such as direct electron transfer, mediator-based systems, redox polymers or conducting polymers and holoenzyme reconstitution, and covers applied areas such as biosensing, biofuel cells, recycling schemes, enzyme competition, light-directed sensing, switchable detection schemes, logical operations by enzyme electrodes and immune sensing.

中文翻译:

PQQ-GDH-结构,功能及其在生物电化学中的应用。

这篇综述总结了PQQ-GDH酶作为糖转化生物催化剂之一的基本特征。重点是膜结合和可溶形式。此外,审查了酶催化的主要原理以及对生理重要性的研究。简要概述了蛋白质工程的发展。然而,主要部分涉及生物电化学中的不同应用领域。这包括用于酶-电极通讯的方法,例如直接电子转移,基于介体的系统,氧化还原聚合物或导电聚合物和全酶重构,并涵盖了诸如生物传感,生物燃料电池,回收方案,酶竞争,光导传感,可切换的检测方案,酶电极的逻辑操作和免疫感应。
更新日期:2020-03-03
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