当前位置: X-MOL 学术NeuroImage › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The pontine-driven somatic gaze tract contributes to affective processing in humans
NeuroImage ( IF 5.7 ) Pub Date : 2020-06-01 , DOI: 10.1016/j.neuroimage.2020.116692
Jing Jun Wong 1 , Dorita H F Chang 2 , Di Qi 1 , Weiwei Men 3 , Jia-Hong Gao 4 , Tatia M C Lee 5
Affiliation  

The relevance of subcortical structures for affective processing is not fully understood. Inspired by the gerbil retino-raphe pathway that has been shown to regulate affective behavior and previous human work showing that the pontine region is important for processing emotion, we asked whether well-established tracts in humans traveling between the eye and the brain stem contribute to functions beyond their conventionally understood roles. Here we report neuroimaging findings showing that optic chiasm-brain stem diffusivity predict responses reflecting perceived arousal and valence. Analyses of subsequent task-evoked connectivity further revealed that visual affective processing implicates the brain stem, particularly the pontine region at an early stage of the cascade, projecting to cortico-limbic regions in a feedforward manner. The optimal model implies that all intrinsic connections between the regions of interest are unidirectional and outwards from the pontine region. These findings suggest that affective processing implicates regions outside the cortico-limbic network. The involvement of a phylogenetically older locus in the pons that has consequences in oculomotor control may imply adaptive consequences of affect detection.

中文翻译:

脑桥驱动的躯体凝视道有助于人类的情感加工

皮层下结构与情感处理的相关性尚不完全清楚。受到沙鼠视网膜-中缝通路的启发,沙鼠视网膜-中缝通路已被证明可以调节情感行为,并且之前的人类工作表明脑桥区域对于处理情绪很重要,我们询问人类在眼睛和脑干之间移动的完善的束是否有助于功能超出了他们通常理解的角色。在这里,我们报告了神经影像学发现,显示视交叉-脑干扩散率预测反映感知觉醒和效价的反应。对后续任务诱发连接的分析进一步表明,视觉情感处理涉及脑干,特别是级联早期的脑桥区域,以前馈方式投射到皮质边缘区域。最佳模型意味着感兴趣区域之间的所有内在连接都是单向的,并且从脑桥区域向外。这些发现表明,情感处理涉及皮质边缘网络之外的区域。脑桥中系统发育较老的基因座对动眼神经控制的影响可能意味着影响检测的适应性后果。
更新日期:2020-06-01
down
wechat
bug