Insufficient sleep has been considered a seizure trigger in people with epilepsy for thousands of years. Here, we reviewed the evidence upon which this axiomatic association might be predicated. After evaluating evidence suggesting insufficient sleep as an EEG activator, we systematically reviewed the literature for longitudinal studies measuring the effect of insufficient sleep on seizure risk. Ultimately, published works designed to prove a causal relationship were of low level of evidence and disagreed with one another. Despite the idea's deep-seated nature, when considering causal evidence only, no conclusion can be made regarding the relationship between insufficient sleep and seizure risk. This article is protected by copyright. All rights reserved.

中文翻译：

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睡眠不足、脑电图激活和癫痫发作风险：重新评估证据

数千年来，睡眠不足一直被认为是癫痫患者癫痫发作的诱因。在这里，我们回顾了可以预测这种公理关联的证据。在评估表明睡眠不足是脑电图激活因素的证据后，我们系统地回顾了纵向研究的文献，这些研究测量了睡眠不足对癫痫发作风险的影响。最终，旨在证明因果关系的已发表作品证据水平低，彼此不一致。尽管这个想法根深蒂固，但仅考虑因果证据时，无法就睡眠不足与癫痫发作风险之间的关系得出结论。本文受版权保护。版权所有。