当前位置:
X-MOL 学术
›
Neuropharmacology
›
论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Genetic causes of PD: A pathway to disease modification.
Neuropharmacology ( IF 4.7 ) Pub Date : 2020-02-29 , DOI: 10.1016/j.neuropharm.2020.108022 M Toffoli 1 , S R L Vieira 1 , A H V Schapira 1
Neuropharmacology ( IF 4.7 ) Pub Date : 2020-02-29 , DOI: 10.1016/j.neuropharm.2020.108022 M Toffoli 1 , S R L Vieira 1 , A H V Schapira 1
Affiliation
The underline neuropathology of Parkinson disease is pleiomorphic and its genetic background diverse. Possibly because of this heterogeneity, no effective disease modifying therapy is available. In this paper we give an overview of the genetics of Parkinson disease and explain how this is relevant for the development of new therapies. This article is part of the special issue entitled 'The Quest for Disease-Modifying Therapies for Neurodegenerative Disorders'.
中文翻译:
PD 的遗传原因:改变疾病的途径。
帕金森病的主要神经病理学是多形性的,其遗传背景多种多样。可能由于这种异质性,没有有效的疾病改善疗法可用。在本文中,我们概述了帕金森病的遗传学,并解释了这与新疗法的开发有何关联。本文是题为“寻求神经退行性疾病的疾病改善疗法”特刊的一部分。
更新日期:2020-03-02
中文翻译:
PD 的遗传原因:改变疾病的途径。
帕金森病的主要神经病理学是多形性的,其遗传背景多种多样。可能由于这种异质性,没有有效的疾病改善疗法可用。在本文中,我们概述了帕金森病的遗传学,并解释了这与新疗法的开发有何关联。本文是题为“寻求神经退行性疾病的疾病改善疗法”特刊的一部分。