Since its innovation in 2006, the dispersive liquid-liquid microextraction (DLLME) method has attracted the attention of analytical chemists in the field of sample preparation. This method has been successfully applied to determine trace amounts of pollutants in various matrices, but the restriction in the choice of suitable disperser and extraction solvents, and high disperser solvent consumption leading to decreased partition coefficients of the analytes between aqueous phase and extractant are its problems. To solve these drawbacks and develop environmentally friendly techniques, various alternatives for the conventional DLLME have been presented. The current review will begin with an introduction to the sample preparation, implementation of DLLME, and its advantages. Then, we focus on its drawbacks, which result mainly from the use of disperser solvent. Afterward, some of the most interesting approaches that have been employed and published until now are reviewed. Finally, an outlook on the future of these techniques will be given.

自2006年创新以来，分散液-液微萃取（DLLME）方法在样品制备领域引起了分析化学家的关注。该方法已成功应用于各种基质中痕量污染物的测定，但是其选择合适的分散剂和萃取溶剂的局限性以及分散剂溶剂消耗高导致分析物在水相和萃取剂之间的分配系数降低是其难题。 。为了解决这些缺点并开发环保技术，已经提出了常规DLLME的各种替代方案。当前的审查将从介绍样品制备，DLLME的实现及其优点开始。然后，我们关注其缺点，这主要是由于使用了分散剂。之后，将回顾到现在为止已经采用和发布的一些最有趣的方法。最后，将对这些技术的未来进行展望。