IMPORTANCE The Postnatal Growth and Retinopathy of Prematurity (G-ROP) Study showed that the addition of postnatal weight gain to birth weight and gestational age detects similar numbers of infants with ROP, but requires examination of fewer infants. OBJECTIVE To determine the incremental cost-effectiveness of screening with G-ROP compared with conventional screening. DESIGN, SETTING AND PARTICIPANTS We built a microsimulation model of a 1-year US birth cohort <32 weeks gestation, using data from the G-ROP study. We obtained resource utilization estimates from the G-ROP dataset and from secondary sources, and test characteristics from the G-ROP cohort. RESULTS Among 78,281 infants nationally, screening with G-ROP detected ~25 additional infants with Type 1 ROP. This was accomplished with 36,233 fewer examinations, in 14,073 fewer infants, with annual cost savings of approximately US$2,931,980 through hospital discharge. CONCLUSIONS Screening with G-ROP reduced costs while increasing the detection of ROP compared with current screening guidelines.

中文翻译：

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从产后生长和 ROP (G-ROP) 研究中评估修改后的早产儿视网膜病变筛查标准的经济影响。

重要性 产后生长和早产儿视网膜病变 (G-ROP) 研究表明，将出生后体重增加与出生体重和胎龄相加可以检测到相似数量的 ROP 婴儿，但需要检查的婴儿更少。目的 确定与传统筛查相比，使用 G-ROP 筛查的成本效益增加。设计、设置和参与者 我们使用来自 G-ROP 研究的数据建立了一个 1 年美国出生队列 < 32 周妊娠的微观模拟模型。我们从 G-ROP 数据集和二级来源获得资源利用率估计，并从 G-ROP 队列中测试特征。结果 在全国 78,281 名婴儿中，使用 G-ROP 筛查发现了约 25 名患有 1 型 ROP 的婴儿。这是通过减少 36,233 次检查、减少 14,073 名婴儿、通过出院每年可节省约 2,931,980 美元的成本。结论 与目前的筛查指南相比，使用 G-ROP 筛查降低了成本，同时提高了 ROP 的检测率。