Abstract There is currently a lack of pathologic data on the novel coronavirus (severe acute respiratory syndrome coronavirus 2) pneumonia, or coronavirus disease 2019 (COVID-19), from autopsy or biopsy. Two patients who recently underwent lung lobectomies for adenocarcinoma were retrospectively found to have had COVID-19 at the time of the operation. These two cases thus provide important first opportunities to study the pathology of COVID-19. Pathologic examinations revealed that apart from the tumors, the lungs of both patients exhibited edema, proteinaceous exudate, focal reactive hyperplasia of pneumocytes with patchy inflammatory cellular infiltration, and multinucleated giant cells. Hyaline membranes were not prominent. Because both patients did not exhibit symptoms of pneumonia at the time of operation, these changes likely represent an early phase of the lung pathology of COVID-19 pneumonia.

中文翻译：

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两名肺癌患者 2019 年早期新型冠状病毒 (COVID-19) 肺炎的肺部病理学

摘要 目前，关于新型冠状病毒（严重急性呼吸系统综合症冠状病毒 2）肺炎或 2019 冠状病毒病（COVID-19）的尸检或活检缺乏病理数据。回顾性发现两名最近因腺癌接受肺叶切除术的患者在手术时患有 COVID-19。因此，这两个案例为研究 COVID-19 的病理学提供了重要的第一次机会。病理检查显示，除肿瘤外，2例患者肺部均有水肿、蛋白样渗出物、局灶性肺细胞反应性增生伴斑片状炎性细胞浸润和多核巨细胞。透明膜不突出。由于两名患者在手术时均未出现肺炎症状，