The selective functionalization of inert C-H bonds is always challenging due to their abundance and large bond dissociation energies. Despite recent advancements, the engagement of inert building blocks for distant functionalization is the most appealing approach for the past decade for the construction of complex molecules. Along with the upsurge of proximal C-H bond activation methods, the presence of directing group or participation of ligand surmounts the challenge of regioselective remote C-H bond transformation. Remote C-H functionalization has emerged as an important tool for the direct synthesis of a variety of natural as well as pharmaceutical products. In this area, chemists are continuously designing and exploring new catalysts, ligands and directing group for the functionalization of C-H bonds which are beyond proximity. Earlier success in this area was limited to meta-position, but recently scientists have come out with new templates which can reach even para-position. The developed catalytic transformations provide access for production of a wide range of value-added products without using classical methods such as Friedel-Craft reactions, Heck coupling, etc., providing atom economical alternate and avoiding the toxic waste generation. On this topic, we have recently published a review article entitled “Distant C-H Activation/Functionalization: A New Horizon of Selectivity beyond Proximity” in the same journal, i.e., Catalysis Reviews: Science and Engineering, 2015, 57(3), 345. In continuation of this article, the present review article will cover the catalytic processes on the mentioned topic mainly developed from 2014 to 2017. The main focus will be on mechanistic pathways and the critical role of template as well as ligands. The purpose of this review is to highlight the recent advancements in remote C-H catalysis and a path ahead.

惰性CH键的选择性功能化始终具有挑战性，因为它们的丰度和键解离能很大。尽管最近取得了一些进步，但在过去的十年中，用于远距离功能化的惰性构建基的参与是构建复杂分子最吸引人的方法。随着近端CH键激活方法的兴起，指导基团的存在或配体的参与克服了区域选择性远程CH键转化的挑战。远程CH功能化已成为直接合成各种天然和药物产品的重要工具。在这一领域，化学家们正在不断设计和探索新的催化剂，配体和用于CH键官能化的直接基团。元位置，但最近科学家提出了新模板，甚至可以达到对位。先进的催化转化无需使用Friedel-Craft反应，Heck偶联等经典方法即可生产多种增值产品，从而提供了原子经济的替代方法，并避免了有毒废物的产生。关于这个主题，我们最近在同一期刊上发表了一篇评论文章，标题为“远距离的CH活化/功能化：超越邻近性的选择性的新视野”，即《催化评论：科学与工程》。，2015，57（3），345。在本文的后续部分，本综述文章将涵盖上述主题的催化过程，该主题主要是从2014年到2017年开发的。主要重点是机械途径和模板的关键作用。以及配体。这篇综述的目的是强调远程CH催化的最新进展和前进的道路。