Intermittent Explosive Disorder (IED), the only psychiatric diagnosis for which affective aggression is the cardinal symptom, is uniquely associated with both a history of childhood abuse and a diagnosis of an alcohol use disorder (AUD). Moreover, both childhood abuse and AUD are associated with increased general aggression and aggression while intoxicated. Yet, no study to date has examined the relative contributions of childhood abuse and AUD to IED, nor their effects on overall and intoxicated aggression among those with and without IED. The following study aimed to fill these gaps. Participants were 493 individuals (68% female; Age M = 26.65) either with (n = 265) or without (psychiatric control group; n = 228) IED. All participants completed a clinical interview to (a) diagnose AUD, IED, and other comorbid psychiatric disorders; (b) assess childhood abuse history; and (c) determine lifetime frequency of overall and intoxicated aggression. Results indicated that a history of childhood abuse, but not AUD status, was uniquely predictive of IED status. With regard to aggression frequency, IED, AUD and childhood abuse were all independently associated with overall aggression, although only those with IED showed increased intoxicated aggression as a function of AUD severity. Overall, these results suggest that a history of childhood abuse may increase the chances of engaging in overall aggression and developing IED, which in turn may increase the association between AUD severity and intoxicated aggression.

中文翻译：

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儿童虐待和酗酒史：与间歇性爆炸性疾病和陶醉的攻击频率有关。

间歇性爆发性疾病（IED）是唯一一种以情感攻击为主要症状的精神病学诊断，它与儿童期虐待史和饮酒障碍（AUD）的诊断都存在独特的关联。此外，儿童时期的虐待和AUD都与普遍的攻击性和陶醉时的攻击性有关。然而，迄今为止，尚无研究研究儿童虐待和澳元对IED的相对贡献，也没有研究其对有或没有IED的儿童对总体和陶醉性侵略的影响。以下研究旨在填补这些空白。参加者有493名（n = 265）有或没有（精神病对照组； n = 228）IED的493人（女性68％；年龄M = 26.65）。所有参与者均完成了临床访谈，以（a）诊断AUD，IED和其他合并症精神病；（b）评估儿童虐待史；（c）确定整体和醉酒侵略的终生频率。结果表明，儿童时期的虐待史（而不是AUD病史）是IED病史的唯一预测。关于攻击频率，IED，AUD和儿童期虐待都与总体攻击独立相关，尽管只有具有IED的人表现出中毒攻击增加是AUD严重程度的函数。总体而言，这些结果表明，儿童时期的虐待史可能会增加进行全面攻击和发展简易爆炸装置的机会，这反过来可能会增加AUD严重程度与陶醉攻击之间的联系。是IED状态的唯一预测。关于攻击频率，IED，AUD和儿童期虐待都与总体攻击独立相关，尽管只有具有IED的人表现出中毒攻击增加是AUD严重程度的函数。总体而言，这些结果表明，儿童时期的虐待史可能会增加进行全面攻击和发展简易爆炸装置的机会，这反过来可能会增加AUD严重程度与陶醉攻击之间的联系。是IED状态的唯一预测。关于攻击频率，IED，AUD和儿童期虐待都与总体攻击独立相关，尽管只有具有IED的人表现出中毒攻击增加是AUD严重程度的函数。总体而言，这些结果表明，儿童时期的虐待史可能会增加进行全面攻击和发展简易爆炸装置的机会，这反过来可能会增加AUD严重程度与陶醉攻击之间的联系。