Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration.,Journal of Cachexia, Sarcopenia and Muscle

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Satellite cell-specific ablation of Cdon impairs integrin activation, FGF signalling, and muscle regeneration.
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2020-02-27 , DOI: 10.1002/jcsm.12563
Ju-Hyeon Bae _{1,

2} , Mingi Hong ₃ , Hyeon-Ju Jeong _{1,

2} , Hyebeen Kim _{1,

2} , Sang-Jin Lee ₄ , Dongryeol Ryu _{1,

5} , Gyu-Un Bae ₄ , Sung Chun Cho ₆ , Young-Sam Lee _{6,

7} , Robert S Krauss ₃ , Jong-Sun Kang _{1,

2,

5}

Affiliation

Perturbation in cell adhesion and growth factor signalling in satellite cells results in decreased muscle regenerative capacity. Cdon (also called Cdo) is a component of cell adhesion complexes implicated in myogenic differentiation, but its role in muscle regeneration remains to be determined.

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