ABSTRACT Fourier transform infrared spectroscopy (FTIR) has been used extensively for chemical characterization of mineralized tissues in the past few decades. FTIR is an ideal technique to analyze chemical structural properties of natural materials, since the frequencies of several vibrational modes of organic and inorganic molecules are active in the infrared. This review discusses the use of FTIR methodology, highlighting the attenuated total reflection (ATR) sampling mode, particularly for characterization of enamel, dentin and bone tissues. Enamel, dentin and bone, are composed of an organic and a mineral phase. The mineral phase is characterized essentially as nonstoichiometric substituted apatite, being the carbonate and phosphate spectral peaks the main representative of these phase. Organic matrix of the post-eruptive enamel is small (∼1% weight (wt)). The dentin and bone organic phases are mainly composed of type I collagen that appears as spectral bands of amide I, amide II, amide III bands. Furthermore, synthetic apatite materials are being designed for total or partial replacement, restoration or augmentation of these biological tissues with FTIR assistance.

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傅里叶变换红外光谱 (FTIR) 应用对牙釉质、牙本质和骨骼的化学表征

摘要 在过去的几十年中，傅里叶变换红外光谱 (FTIR) 已被广泛用于矿化组织的化学表征。FTIR 是分析天然材料化学结构特性的理想技术，因为有机和无机分子的几种振动模式的频率在红外线中是活跃的。本综述讨论了 FTIR 方法的使用，重点介绍了衰减全反射 (ATR) 采样模式，特别是用于表征牙釉质、牙本质和骨组织。牙釉质、牙本质和骨骼由有机相和矿物相组成。矿物相的特征基本上是非化学计量取代的磷灰石，碳酸盐和磷酸盐光谱峰是这些相的主要代表。喷发后牙釉质的有机基质很小（约 1% 重量 (wt)）。牙本质和骨有机相主要由I型胶原组成，表现为酰胺I、酰胺II、酰胺III谱带。此外，合成磷灰石材料正在设计用于在 FTIR 的帮助下完全或部分替换、修复或增强这些生物组织。