Background One of the core symptoms of behavioural variant frontotemporal dementia (bvFTD) is the early loss of social cognitive abilities, which has a deteriorating impact on everyday interaction and the quality of dyadic relationships. Marte Meo® (MM) counselling is a video-based intervention that aims to maintain or improve the quality of dyadic relationships. This non-randomized mixed-method study aimed to evaluate the feasibility of the intervention in practice with primary carers of persons with bvFTD as well as the feasibility of a future confirmatory trial. Methods A pilot effect study with a quasi-experimental, one-group, pre-post design and double pre-measurement was conducted. Data were collected at three time points (t0, t1 after 2 weeks, and t2 after 6 weeks) using videography and several measurement instruments. Between t1 and t2, each primary carer received five MM counselling sessions. The outcomes included positive and negative affect, behavioural and psychological symptoms in dementia (BPSD), the interpersonal abilities of the person with dementia, the sensitivity and distress of the primary carers due to BPSD, the manageability of BPSD, the personal goal attainment by means of MM counselling, and the quality of the dyadic relationships. The pilot process evaluation focused on the primary carers' and the interventionist's perceived benefits and perceptions of the intervention process using questionnaires and interviews. Results Five dyads were enrolled. Regarding the feasibility of the intervention, MM counselling seems to be appropriate and useful for the target group. Although the recruitment of persons with reliable bvFTD diagnoses was very time consuming and complex, the intervention was well accepted by the dyads, and regarding goal attainment, all carers benefited as much or even more than they expected. The study also showed that the benefits of MM counselling depend on whether the primary carer has accepted his/her relative's dementia. Regarding the feasibility of a future confirmatory trial, certain outcomes, particularly positive affect, distress due to BPSD, and the quality of the dyadic relationship, seem to be appropriate for describing possible effects. Conclusion Overall, the intervention seems feasible for this target group. A future confirmatory trial should be planned as a multicentre pilot trial with an extension option. Trial registration DRKS00014377. Registered retrospectively on April 11, 2018.

中文翻译：

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Marte Meo® 咨询与行为变异额颞叶痴呆患者及其主要照顾者 (AMEO-FTD) 的应用——一项非随机混合方法可行性研究。

背景 行为变异性额颞叶痴呆 (bvFTD) 的核心症状之一是社会认知能力的早期丧失，这对日常互动和二元关系的质量产生了恶化的影响。Marte Meo® (MM) 咨询是一种基于视频的干预措施，旨在维持或提高二元关系的质量。这项非随机混合方法研究旨在评估在实践中对 bvFTD 患者的主要照顾者进行干预的可行性以及未来验证性试验的可行性。方法采用准实验、一组、事前设计和双重事前测量的先导效果研究。使用摄像和几种测量仪器在三个时间点（t0、2 周后 t1 和 6 周后 t2）收集数据。在 t1 和 t2 之间，每个主要照顾者都接受了五次 MM 咨询课程。结果包括正面和负面影响、痴呆症的行为和心理症状 (BPSD)、痴呆症患者的人际交往能力、主要照顾者对 BPSD 的敏感性和痛苦、BPSD 的可管理性、个人目标的实现MM咨询的质量，以及二元关系的质量。试点过程评估侧重于主要照顾者和干预者的感知利益以及使用问卷和访谈对干预过程的看法。结果 5 对 dyads 被录取。关于干预的可行性，MM 咨询似乎对目标群体是合适和有用的。尽管招募具有可靠 bvFTD 诊断的人员非常耗时且复杂，但该干预被二人组很好地接受，并且在目标实现方面，所有护理人员都受益于他们的预期甚至更多。该研究还表明，MM 咨询的好处取决于主要照顾者是否接受了他/她亲属的痴呆症。关于未来验证性试验的可行性，某些结果，特别是积极影响、BPSD 引起的痛苦以及二元关系的质量，似乎适合描述可能的影响。结论 总体而言，干预似乎对这个目标群体是可行的。未来的验证性试验应计划为具有扩展选项的多中心试验性试验。试用注册DRKS00014377。