Background

Rotating night shift contributes to the development of metabolic syndrome and relevant diseases. However, the contribution of different aspects of rotating night shift is rarely studied.

Aim

To investigate the association of frequency and duration of rotating night shift with metabolic parameters.

Methods

A cross-sectional study was conducted in nurses. Socio-demographic characteristics, duration and frequency of rotating night shift, and metabolic parameters including body mass index (BMI), fasting blood glucose(FBG), blood pressure (BP), triglyceride, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C) and high density lipoprotein cholesterol (HDL-C), were collected. Sleep quality and perceived stress were assessed with Pittsburgh Sleep Quality Index and Perceived Stress Scale respectively. Ratio of rotating night shift years to age (RRSYA) was calculated to present cumulative effect. Metabolic parameters were log-transformed and z-transformed in sequence. Multiple linear regressions were applied to explore the effect of frequency and RRSYA on metabolic parameters. Mediation analysis was used to estimate potential mediating effect of sleep quality and perceived stress.

Results

Frequency of rotating night shift was significantly associated with elevated FBG and BMI, and decreased LDL-C. RRSYA was significantly associated with higher BMI, TC, LDL-C, BP and FBG. Sleep quality exhibited significant mediating effect between rotating night shift features and FBG and BMI.

Conclusions

Our results suggest that frequency and RRSYA are associated with metabolic profile alterations, but the effects are different. Sleep quality appears to be an important mediator of the night shift’s metabolic effect. Proper shift arrangement and sleep quality assurance may reduce the negative metabolic changes.

中文翻译：

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夜班轮换的频率和持续时间均与代谢参数有关：一项横断面研究。

背景

夜班轮班有助于代谢综合征和相关疾病的发展。然而，很少研究旋转夜班的不同方面的贡献。

目标

调查频率和旋转夜班持续时间与代谢参数的关联。

方法

在护士中进行了横断面研究。社会人口统计学特征，轮换夜班的持续时间和频率以及包括体重指数（BMI），空腹血糖（FBG），血压（BP），甘油三酸酯，总胆固醇（TC），低密度脂蛋白胆固醇（收集LDL-C和高密度脂蛋白胆固醇（HDL-C）。睡眠质量和感知压力分别通过匹兹堡睡眠质量指数和感知压力量表进行评估。计算夜班轮换年龄与年龄之比（RRSYA）以显示累积效应。代谢参数按顺序进行对数转换和z转换。应用多元线性回归来探讨频率和RRSYA对代谢参数的影响。

结果

夜班频率与FBG和BMI升高以及LDL-C降低显着相关。RRSYA与较高的BMI，TC，LDL-C，BP和FBG显着相关。睡眠质量在旋转夜班功能与FBG和BMI之间表现出显着的中介作用。

结论

我们的结果表明，频率和RRSYA与代谢谱改变有关，但影响不同。睡眠质量似乎是夜班代谢作用的重要调节剂。适当的轮班安排和睡眠质量保证可以减少新陈代谢的负面变化。