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Practical Preparation of Cyclopropenone 1,3-Propanediol Ketal
Synthesis ( IF 2.6 ) Pub Date : 2020-02-24 , DOI: 10.1055/s-0039-1690830
Florian F. Mulks , Robin Heckershoff , Marc Zimmer , A. Stephen K. Hashmi

Cyclopropenone 1,3-propanediol ketal is an increasingly versatile building block for the introduction of various C3 and dioxaspiro units due to the emergence of numerous methodologies for the application of strained hydrocarbons. This Practical Synthetic Procedure gives an updated synthesis for a basic ketal of cyclopropenone with lowered solvent toxicity and a detailed step-by-step guide for the safe production of potassium amide in liquid ammonia and for its application in the synthesis of the cyclopropene ring.

中文翻译:

环戊烯酮1,3-丙二醇缩酮的实用制备

环丙烯酮1,3-丙二醇缩酮是一种越来越多用途的结构单元,可用于引入各种C 3和二氧杂螺环单元,这是因为出现了许多应用碳氢化合物的方法。该实用的合成程序提供了具有降低的溶剂毒性的环丙烯酮基本缩酮的最新合成方法,以及有关在液氨中安全生产酰胺钾及其在环丙烯环合成中的应用的详细分步指南。
更新日期:2020-02-25
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