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A guide to naming human non-coding RNA genes.
The EMBO Journal ( IF 11.4 ) Pub Date : 2020-02-24 , DOI: 10.15252/embj.2019103777
Ruth L Seal 1, 2 , Ling-Ling Chen 3 , Sam Griffiths-Jones 4 , Todd M Lowe 5 , Michael B Mathews 6 , Dawn O'Reilly 7 , Andrew J Pierce 8 , Peter F Stadler 9, 10, 11, 12, 13 , Igor Ulitsky 14 , Sandra L Wolin 15 , Elspeth A Bruford 1, 2
Affiliation  

Research on non-coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene. The HUGO Gene Nomenclature Committee (HGNC, www.genenames.org) is the only group with the authority to approve symbols for human genes. The HGNC works with specialist advisors for different classes of ncRNA to ensure that ncRNA nomenclature is accurate and informative, where possible. Here, we review each major class of ncRNA that is currently annotated in the human genome and describe how each class is assigned a standardised nomenclature.

中文翻译:

命名人类非编码RNA基因的指南。

非编码RNA(ncRNA)的研究是一个迅速扩展的领域。为ncRNA基因提供正式的基因符号和名称会给潜在的混乱带来秩序,因为它允许有关每个基因的明确沟通。HUGO基因命名委员会(HGNC,www.genenames.org)是唯一有权批准人类基因符号的组织。HGNC与专家顾问针对不同类别的ncRNA进行合作,以确保ncRNA命名在可能的情况下是准确和有用的。在这里,我们回顾了目前在人类基因组中注释的ncRNA的每个主要类别,并描述了如何为每个类别分配标准化的命名法。
更新日期:2020-03-19
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