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Differential sensitivity of human islets from obese versus lean donors to chronic high glucose or palmitate.
Journal of Diabetes ( IF 4.5 ) Pub Date : 2020-03-06 , DOI: 10.1111/1753-0407.13026
Françoise Castex 1 , Jeremy Leroy 1 , Christophe Broca 2 , Karima Mezghenna 1 , Flore Duranton 1, 3 , Vanessa Lavallard 4 , Fanny Lebreton 3 , René Gross 1 , Anne Wojtusciszyn 2 , Anne-Dominique Lajoix 1
Affiliation  

Due to the shortage of multi‐organ donors, human pancreatic islet transplantation has now been extended to islets originating from obese subjects. In this study, our aim is to compare the respective sensitivity of human islets from lean vs obese donors to chronic high glucose or high palmitate.

中文翻译:

肥胖和瘦供者的人类胰岛对慢性高葡萄糖或棕榈酸酯的敏感性差异。

由于缺乏多器官捐献者,人类胰岛移植现已扩展到源自肥胖受试者的胰岛。在这项研究中,我们的目的是比较来自瘦和肥胖供者的人类胰岛对慢性高血糖或高棕榈酸酯的敏感性。
更新日期:2020-03-06
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