The transmission of airborne diseases in animals poses great risks to animal safety with potential significant economic losses. In this study, we report on the use of a dielectric barrier discharge (DBD) for in‐flight inactivation of an airborne aerosolized porcine reproductive and respiratory syndrome virus. The infectivity of the sampled virus downstream compared to upstream of the DBD reactor as determined by the TCID₅₀ method showed a ∼3.5 log₁₀ reduction in the virus titer. Independent testing of the viral genome by the reverse‐transcription quantitative real‐time polymerase chain reaction method confirmed the inactivation with minimal filtering effects. Both short‐lived species such as and and peroxynitrous acid (ONOOH) chemistry at low pH in the virus‐laden droplets are suggested to be responsible for the observed inactivation.

中文翻译：

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使用大气压空气等离子体快速灭活机载猪繁殖与呼吸综合征病毒

动物中空气传播疾病的传播对动物安全构成了巨大风险，并可能造成重大的经济损失。在这项研究中，我们报告了使用介电屏障放电（DBD）在空中灭活气溶胶化的猪繁殖与呼吸综合征病毒的过程。通过TCID ₅₀方法确定，与DBD反应器上游相比，下游采样病毒的传染性表明病毒效价降低了约3.5 log ₁₀。通过逆转录实时定量聚合酶链反应方法对病毒基因组进行独立测试，证实了灭活作用具有最小的过滤作用。两种短命物种，例如和 建议在载有病毒的液滴中使用低pH值的过氧亚硝酸（ONOOH）化学物来观察到失活。