Biomarkers are well established for the diagnosis of myocardial infarction, heart failure and cardiac fibrosis. Different papers on cardiac biomarker evolution during exercise have been published in the literature and generally show mild to moderate elevations. However, the mechanism responsible for these elevations, reflecting physiological or even pathophysiological changes, still has to be clearly elucidated. There are also indications of higher cardiac risk in poorly trained athletes than in well-trained athletes. Whether regular repetition of intensive exercise might lead, in the longer term, to fibrosis and heart failure remains to be determined. In this review, we summarized the main research about the effects of intense exercise (in particular, running) on cardiac biomarkers (including troponins, natriuretic peptides, etc.). We found that cardiac fibrosis biomarkers seemed to be the most informative regarding the biological impact of intense physical activity.

中文翻译：

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激烈的体育锻炼和心脏生物标志物。

生物标志物已经很好地用于诊断心肌梗塞，心力衰竭和心脏纤维化。关于运动过程中心脏生物标志物进化的不同论文已在文献中发表，并且通常显示轻度至中度升高。但是，仍然必须清楚地阐明造成这些海拔升高的机制，反映出生理乃至病理生理的变化。还有迹象表明，训练有素的运动员比受过训练的运动员有更高的心脏风险。从长远来看，定期重复进行剧烈运动是否会导致纤维化和心力衰竭尚待确定。在这篇综述中，我们总结了关于剧烈运动（特别是跑步）对心脏生物标志物（包括肌钙蛋白，利钠肽等）影响的主要研究。