Biological membranes play key roles in cell life, but their intrinsic complexity motivated the study and development of artificial lipid membranes with the primary aim to reconstitute and understand the natural functions in vitro. Porous-supported lipid membrane (pSLM) has emerged as a flexible platform for studying the surface chemistry of the cell due to their high stability and fluidity, and their ability to study the transmembrane process of the molecules. In this review, the pSLM, for the first time, to our knowledge, was divided into three types according to the way of the porous materials support the lipid membrane, containing the lipid membrane on the pores of the porous materials, the lipid membrane on both sides of the porous materials, the lipid membrane in the pores of the porous materials. All of these pSLMs were systematically elaborated from several aspects, including the substrates, formation, and characterization. Meanwhile, the advantages and disadvantages of each model membranes were summarized. Finally, suggestions for selecting appropriate pSLM and future directions in this area are discussed.

中文翻译：

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由平面多孔基质支撑的脂质膜。

生物膜在细胞生命中起着关键作用，但其固有的复杂性激发了人工脂质膜的研究和开发，其主要目的是重建和了解体外的自然功能。多孔支撑脂质膜（pSLM）由于其高稳定性和流动性以及研究分子的跨膜过程的能力而成为研究细胞表面化学的灵活平台。在这篇综述中，据我们所知，pSLM首次根据多孔材料支持脂质膜的方式分为三种类型，即在多孔材料的孔中包含脂质膜，在多孔材料的两侧，脂质膜在多孔材料的孔中。所有这些pSLM都从多个方面进行了系统地阐述，包括底物，形成和表征。同时，总结了每种型号膜的优缺点。最后，讨论了选择合适的pSLM的建议以及该领域的未来方向。