OBJECTIVE To determine if prolonging gavage feedings in infants for ≥60 min is associated with decreased gastroesophageal reflux (GER) compared with bolus feeding using multiple-channel intraluminal impedance with pH probe (MII-pH). STUDY DESIGN Retrospective analysis of infants who underwent MII-pH between October 2009 and July 2018 and received gavage feedings. Infants were divided into two groups: bolus (<30 min) or prolonged (≥60 min). Symptoms, number of reflux events and percent time pH < 4 was compared. RESULT Fifty-eight infants underwent evaluation. Thirty-one (54%) received bolus gavage feedings and 27 (46%) received prolonged feedings. Groups differed in postmenstrual age. Total reflux episodes were significantly lower with prolonged feeding (median 19 vs. 28 episodes, p = 0.015), with no difference in acid exposure time. There was no significant difference in GER symptoms between the two groups. CONCLUSION Prolongation of gavage feedings was associated with decreased total numbers of GER events without reduction in GER symptoms.

中文翻译：

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延长管饲时间以减少婴儿胃食管反流。

目的 确定与使用带 pH 探针的多通道管腔内阻抗 (MII-pH) 的推注喂养相比，延长婴儿灌胃喂养 60 分钟以上是否与减少胃食管反流 (GER) 相关。研究设计 对 2009 年 10 月至 2018 年 7 月期间接受 MII-pH 并接受管饲喂养的婴儿进行回顾性分析。婴儿分为两组：推注（<30 分钟）或延长（≥60 分钟）。比较了症状、反流事件的数量和 pH < 4 的时间百分比。结果 58 名婴儿接受了评估。31 人 (54%) 接受了快速灌胃喂养，27 人 (46%) 接受了长时间喂养。各组的经后年龄不同。长期喂养后总反流发作显着降低（中位数 19 次对 28 次发作，p = 0.015），酸暴露时间没有差异。两组之间的GER症状没有显着差异。结论 延长管饲喂养与 GER 事件总数减少相关，但 GER 症状没有减少。