Neurotransmitters play critical roles in the developing nervous system. Among the neurotransmitters, norepinephrine (NE) is in particular postulated to be an important regulator of brain development. NE is expressed during early stages of development and is known to regulate both the development of noradrenergic neurons and the development of target areas. NE participates in the shaping and the wiring of the nervous system during the critical periods of development, and perturbations in this process can alter the brain's developmental trajectory, which in turn can cause long-lasting and even permanent changes in the brain function and behavior later in life. Here we will briefly review evidence for the role of noradrenergic system in neurodevelopmental processes and will discuss about the potential disruptors of noradrenergic system during development and their behavioral consequences.

中文翻译：

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去甲肾上腺素，神经发育和行为。

神经递质在神经系统发育中起关键作用。在神经递质中，去甲肾上腺素（NE）特别被认为是大脑发育的重要调节剂。NE在发育的早期阶段表达，并且已知它可以调节去甲肾上腺素能神经元的发育和靶区域的发育。NE在发育的关键时期参与神经系统的塑形和布线，并且在此过程中的扰动会改变大脑的发育轨迹，进而导致以后大脑功能和行为的持久乃至永久性变化。在生活中。