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Current Advances in Separation and Purification of Second-Generation Lactic Acid
Separation and Purification Reviews ( IF 5.4 ) Pub Date : 2019-04-01 , DOI: 10.1080/15422119.2019.1590412
Regiane Alves De Oliveira 1 , Maria Alexandri 2 , Andrea Komesu 3 , Joachim Venus 2 , Carlos Eduardo Vaz Rossell 4 , Rubens Maciel Filho 1
Affiliation  

Lactic acid is an important chemical as starting chiral material in various applications. It has increased value in the global market. Different studies have presented the possibility to obtain rich lactic acid solutions with high isomeric purity (S-form) from second-generation (2G) feedstocks. The used downstream process is crucial, not only in terms of the overall cost but also for the achievement of high product purity, suitable for high-value applications. This review provides an overview of the current state-of-the-art on the separation and purification methods of lactic acid derived from the fermentation of second-generation feedstocks. The traditional precipitation method, solvent extraction, affinity-related processes, membrane separation, reaction-separation systems, salting-out extraction and molecular distillation are the main processes investigated so far. The different approaches are discussed in terms of lactic acid recovery yield and purity as well as their environmental impact.



中文翻译:

第二代乳酸的分离纯化研究进展

乳酸是在各种应用中作为手性原料的重要化学物质。它在全球市场上具有增加的价值。不同的研究提出了从第二代(2G)原料中获得高异构体纯度(S型)的富乳酸溶液的可能性。所用的下游工艺至关重要,不仅在总体成本方面,而且对于实现适用于高价值应用的高产品纯度也至关重要。这篇综述概述了第二代原料发酵产生的乳酸的分离和纯化方法的最新技术。传统的沉淀方法,溶剂萃取,与亲和力相关的过程,膜分离,反应分离系统,盐析提取和分子蒸馏是迄今为止研究的主要过程。就乳酸回收率,纯度及其对环境的影响,讨论了不同的方法。

更新日期:2020-04-20
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