当前位置: X-MOL 学术Trends Biochem. Sci. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Nucleoporin Condensates Drive Nuclear Pore Complex Assembly in Oocytes.
Trends in Biochemical Sciences ( IF 13.8 ) Pub Date : 2020-02-13 , DOI: 10.1016/j.tibs.2020.01.009
George W Mobbs 1 , André Hoelz 1
Affiliation  

Oocytes stockpile nuclear pore complexes (NPCs) in cytoplasmic membrane sheets called annulate lamellae (AL) in preparation for rapid cell cycles during embryogenesis. Recently, Hampoelz et al. reported that AL–NPC assembly depends on the coordinated formation, transport, and interaction of biomolecular condensates containing distinct sets of nucleoporins.



中文翻译:

核蛋白凝聚物驱动卵母细胞中的核孔复合体组装。

卵母细胞在称为环状薄片(AL)的胞质膜片中储存核孔复合物(NPC),以为胚胎发生期间的快速细胞周期做准备。最近,Hampoelz等人。报告指出,AL-NPC的组装取决于包含不同核仁素的生物分子缩合物的协调形成,运输和相互作用。

更新日期:2020-02-20
down
wechat
bug