Chronic kidney disease is inevitably associated with the proliferation of fibroblasts following injury of the tubular system and collagen deposition in the interstitial tissue. To date, renal fibrosis has been hard to detect without histologic tissue examination. In this issue of Kidney International, Baues et al. introduce a novel technology for noninvasive detection of renal fibrosis using a multimodal optical approach with the fluorescent-labelled collagen-binding agent CNA35-Cy7.

中文翻译：

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从来没有受伤的伤疤。

慢性肾病不可避免地与肾小管系统损伤和间质组织胶原沉积后的成纤维细胞增殖有关。迄今为止，没有组织学检查很难发现肾纤维化。在这一期的国际肾脏组织中，Baues等人。介绍一种使用多模式光学方法与荧光标记的胶原结合剂CNA35-Cy7进行无创检测肾纤维化的新技术。