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Effect of vessel preservation on splenic volume and function in patients with spleen preserving distal pancreatectomies.
HPB ( IF 2.9 ) Pub Date : 2020-02-17 , DOI: 10.1016/j.hpb.2020.01.012
Lavanya Yohanathan 1 , Benjamin P T Loveday 2 , Nishaan Brar 3 , Paul D Greig 4 , Ian D McGilvray 4 , Carol-Anne Moulton 4 , Steven Gallinger 4 , Alice C Wei 5 , Sean P Cleary 1
Affiliation  

BACKGROUND Spleen preservation during distal pancreatectomy (SpDP) can be accomplished by a variety of surgical approaches, but the impact on spleen function is unknown. This study aimed to compare spleen volume, function and complications between patients who underwent vessel sparing (VSDP) vs. vessel ligating (Warshaw, WDP) SpDP. METHODS All patients who underwent SpDP at the Toronto General Hospital from 2006 to 2015 were included. Primary outcomes were pre- and post-operative spleen volumes and contrast enhancement on CT, hematologic parameters, and spleen-related complications. RESULTS 82 patients underwent SpDP with median follow up of 20.4 months. Splenic volumes were able to be calculated on 44 patients (VSDP n = 8, WDP n = 36). There was no difference between WDP and VSDP in operative duration, blood loss, hospital length of stay, or Clavien-Dindo ≥3 complication rate. Spleen volumes did not differ from baseline in either group. On postoperative imaging more WDP patients had areas of splenic hypoperfusion (p = 0.032). These differences resolved by 3 months after surgery, there were no instances of long term infectious or bleeding complications related to poor splenic function or gastric varices. CONCLUSION Both WDP and VSDP achieve splenic preservation. Neither technique resulted in clinically apparent spleen related complications. There is no difference in splenic volume and function in the short/long term.

中文翻译:

保留血管对保留脾脏远端胰腺切除术患者脾脏体积和功能的影响。

背景 胰腺远端切除术 (SpDP) 期间的脾脏保留可以通过多种手术方法完成,但对脾脏功能的影响尚不清楚。本研究旨在比较接受血管保留 (VSDP) 与血管结扎 (Warshaw, WDP) SpDP 的患者之间的脾脏体积、功能和并发症。方法 纳入 2006 年至 2015 年在多伦多总医院接受 SpDP 的所有患者。主要结果是术前和术后脾脏体积和 CT 对比增强、血液学参数和脾脏相关并发症。结果 82 名患者接受了 SpDP,中位随访时间为 20.4 个月。能够计算 44 名患者的脾体积(VSDP n = 8,WDP n = 36)。WDP和VSDP在手术时间、失血量、住院时间、或 Clavien-Dindo ≥3 并发症发生率。在任一组中,脾体积与基线没有差异。在术后影像学上,更多的 WDP 患者有脾脏低灌注区域(p = 0.032)。这些差异在术后 3 个月消失,没有与脾功能差或胃静脉曲张相关的长期感染或出血并发症。结论 WDP 和 VSDP 均实现了脾脏保留。这两种技术都没有导致临床上明显的脾相关并发症。短期/长期脾脏体积和功能没有差异。没有与脾功能差或胃静脉曲张相关的长期感染或出血并发症的病例。结论 WDP 和 VSDP 均实现了脾脏保留。这两种技术都没有导致临床上明显的脾相关并发症。短期/长期脾脏体积和功能没有差异。没有与脾功能差或胃静脉曲张相关的长期感染或出血并发症的病例。结论 WDP 和 VSDP 均实现了脾脏保留。这两种技术都没有导致临床上明显的脾相关并发症。短期/长期脾脏体积和功能没有差异。
更新日期:2020-02-17
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