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Solvent‐Free Generation of Foamed Microcapillary Films with a Dual Network of Interconnected Pores and Internal Channels
Macromolecular Materials and Engineering ( IF 3.9 ) Pub Date : 2020-02-19 , DOI: 10.1002/mame.201900768
Jianxiang Zhao 1 , Zhongbin Xu 1 , Suxia Zheng 2 , Cong Liu 1 , Junfeng Liu 1 , Hao Pei 3
Affiliation  

A dual‐pore network is favored in applications such as tissue engineering scaffolds. In this paper, foamed microcapillary films (FMCFs) are prepared based on a poly(lactic acid)/poly(butylene succinate) blend using melt extrusion and batch foaming with supercritical carbon dioxide. Such films are characterized by multiple hollow microcapillaries (diameter of 100–360 µm) connected with cells (size of 3–194 µm, open‐cell content of over 80%) within the scaffold. By plugging the ends of the MCF before foaming, the formation of a solid skin layer is successfully avoided. Furthermore, the diameter of the microcapillaries of an FMCF can be adjusted using the designed foaming strategy. The effects of the foaming condition on the FMCF foaming behavior are also investigated. When other conditions are fixed, the foaming behavior changes dramatically when the foaming temperature changes within the range of 120–123 °C.

中文翻译:

具有互连的孔和内部通道的双网络的无溶剂的发泡微毛细管膜生成

双孔网络在组织工程支架等应用中受到青睐。在本文中,基于聚乳酸/聚丁二酸丁二酯的共混物,通过熔融挤出和超临界二氧化碳间歇发泡制备了泡沫微毛细管薄膜(FMCF)。这种膜的特征是多个空心微毛细管(直径为100–360 µm)与支架内的细胞(尺寸为3–194 µm,开孔含量超过80%)相连。通过在发泡之前堵塞MCF的末端,可以成功避免形成固体表皮层。此外,可以使用设计的发泡策略来调节FMCF的微毛细管直径。还研究了发泡条件对FMCF发泡行为的影响。在其他条件固定的情况下,
更新日期:2020-03-12
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