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Ligand-Free Palladium-Catalyzed Mizoroki-Heck Reaction to Synthesize Valuable α-Trifluoromethylacrylates
Journal of Fluorine Chemistry ( IF 1.9 ) Pub Date : 2020-02-19 , DOI: 10.1016/j.jfluchem.2020.109483
Pan Xiao , Claire Schlinquer , Xavier Pannecoucke , Samuel Couve-Bonnaire , Jean-Philippe Bouillon

α-Trifluoromethylacrylates were synthesized using efficient ligand-free palladium catalyzed Mizoroki-Heck reaction. With the alkyl trifluoromethylacrylates used as substrates, different catalytic systems were explored including Pd/C as a catalyst. Good to excellent yields were obtained with good chemical tolerance



中文翻译:

无配体钯催化的Mizoroki-Heck反应合成有价值的α-三氟甲基丙烯酸酯

使用有效的无配体钯催化的Mizoroki-Heck反应合成了α-三氟甲基丙烯酸酯。以烷基三氟甲基丙烯酸烷基酯为底物,探索了包括Pd / C作为催化剂的不同催化体系。以良好的化学耐受性获得了良好的优良收率

更新日期:2020-02-20
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