Spatial repositioning of genes in nuclear space has been extensively linked to regulation of gene expression, but the mechanisms behind this directed movement have remained uncertain. In this issue of Developmental Cell, Wang et al. (2020) describe a nuclear actin-myosin-based pathway driving the movement of activated genes to the nuclear periphery.

中文翻译：

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基因如何移动：激活基因的空间重定位是由基于核肌动蛋白的途径驱动的。

基因在核空间中的空间重新定位已与基因表达的调节广泛相关，但这种定向运动背后的机制仍不确定。在本期《发育细胞》中，Wang等人。（2020）描述了一种基于核肌动蛋白-肌球蛋白的途径，驱动活化基因向核外围移动。