Alkene difunctionalization represents one of the most efficient methods to synthesize highly functionalized molecules from simple and readily available starting materials. In contrast to the well-established redox-neutral alkene difunctionalization reactions, reductive alkene difunctionalization, which simultaneously introduces two electrophiles on both sides of the double bond, has been much less developed, especially in enantioselective manner. This review summarizes recent advances in the nickel-catalyzed reductive difunctionalization of alkenes and highlights the enantioselective transformations.

中文翻译：

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镍催化烯烃的还原双官能化

烯烃双官能化代表了从简单易得的起始原料合成高度官能化分子的最有效方法之一。与公认的氧化还原-中性烯烃双官能化反应相反，还原性烯烃双官能化同时在双键的两面引入两个亲电试剂，特别是以对映选择性的方式开发。这篇综述总结了镍催化的烯烃的还原双官能化的最新进展，并突出了对映选择性的转化。