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Predicting survival in infants born at <27 weeks gestation admitted to an all referral neonatal intensive care unit: a pilot study.
Journal of Perinatology ( IF 2.9 ) Pub Date : 2020-02-20 , DOI: 10.1038/s41372-020-0629-x
Nikou Pishevar 1 , Omid Fathi 2, 3 , Carl H Backes 1, 2, 3 , Edward G Shepherd 2, 3 , Leif D Nelin 1, 2, 3
Affiliation  

BACKGROUND There are no available predictive models for survival in extremely preterm (EP) infants admitted to a referral Level IV neonatal intensive care unit (NICU) after the first day of life (DOL). OBJECTIVE To determine if there are clinical variables present at admission that are associated with survival in an outborn EP population. STUDY DESIGN Data were analyzed from EP infants admitted before DOL 100 from 2008 to 2016 (n = 744). RESULTS We found that prophylactic indomethacin (OR 1.98 (1.20-3.25) p = 0.007), admit DOL (OR 1.05 (1.02-1.08) p < 0.001), and birth in Franklin County, (OR 2.02 (95% CI, 1.04-3.90) p = 0.04) were all associated with survival. Using ROC analysis, the area under the curve for the provisional survival score was 0.69 (95% CI, 0.64-0.75; p < 0.0001). CONCLUSIONS There are factors on admission to a referral Level IV NICU associated with survival in EP patients.

中文翻译:

预测入住所有转诊新生儿重症监护病房的小于 27 周出生婴儿的存活率:一项初步研究。

背景 对于出生后第一天 (DOL) 转诊至 IV 级新生儿重症监护病房 (NICU) 的极早产 (EP) 婴儿,尚无可用的生存预测模型。目的 确定入院时是否存在与出生 EP 人群的生存相关的临床变量。研究设计数据分析了 2008 年至 2016 年 DOL 100 之前入院的 EP 婴儿(n = 744)。结果 我们发现,预防性使用吲哚美辛(OR 1.98 (1.20-3.25) p = 0.007)、接受 DOL(OR 1.05 (1.02-1.08) p < 0.001)和在富兰克林县出生(OR 2.02 (95% CI, 1. 3.90) p = 0.04) 都与生存相关。使用 ROC 分析,临时生存评分的曲线下面积为 0.69(95% CI,0.64-0.75;p < 0.0001)。
更新日期:2020-02-20
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