当前位置: X-MOL 学术Process Biochem. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Synthesized β-cyclodextrin modified graphene oxide (β-CD-GO) composite for adsorption of cadmium and their toxicity profile in cervical cancer (HeLa) cell lines
Process Biochemistry ( IF 4.4 ) Pub Date : 2020-06-01 , DOI: 10.1016/j.procbio.2020.02.014
Melvin S. Samuel , E. Selvarajan , Kalidass Subramaniam , Thangavel Mathimani , Sangeetha Seethappan , Arivalagan Pugazhendhi

Abstract In the current study, a composite material was constructed using β-cyclodextrin/graphene oxide (β-CD-GO) and was then applied for the purpose of eliminating cadmium (Cd) from aqueous solution. The synthesized β-CD-GO composite material was then subjected to characterization using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The batch study was conducted for the purpose of removing Cd(II). The results of the study revealed that the β-CD-GO composite material demonstrated a high adsorption capacity of 196 mg/g of Cd(II) at pH 7.0. Further, the adsorption of Cd(II) on the β-CD-GO followed pseudo second-order kinetics and equilibrium adsorption data, which fitted well to the Langmuir isotherm model. The evaluation of the toxicity of the synthesized β-CD-GO composite material was done by the examination of the cervical cancer (HeLa) cell lines. Increasing concentration of β-CD-GO composite material (50 μg to 200 μg) leads to a decline in the percentage of cell viability as from 74 % to 25 %. This study has suggested that the β-CD-GO could play an efficient and beneficial source of the adsorbent for the purpose of eliminating Cd(II) from aqueous solution.

中文翻译:

合成的 β-环糊精修饰氧化石墨烯 (β-CD-GO) 复合材料用于吸附镉及其在宫颈癌 (HeLa) 细胞系中的毒性特征

摘要 在目前的研究中,使用β-环糊精/氧化石墨烯(β-CD-GO)构建了一种复合材料,然后将其应用于去除水溶液中的镉(Cd)。然后使用傅里叶变换红外光谱 (FTIR)、X 射线衍射 (XRD)、扫描电子显微镜 (SEM) 和透射电子显微镜 (TEM) 对合成的 β-CD-GO 复合材料进行表征。进行批量研究是为了去除 Cd(II)。研究结果表明,β-CD-GO 复合材料在 pH 7.0 时表现出 196 mg/g Cd(II) 的高吸附容量。此外,Cd(II) 在 β-CD-GO 上的吸附遵循伪二级动力学和平衡吸附数据,这与朗缪尔等温线模型非常吻合。通过对宫颈癌(HeLa)细胞系的检查,对合成的β-CD-GO复合材料的毒性进行了评价。增加 β-CD-GO 复合材料的浓度(50 μg 至 200 μg)导致细胞活力百分比从 74% 下降至 25%。该研究表明,β-CD-GO 可以作为一种有效且有益的吸附剂来源,用于从水溶液中去除 Cd(II)。
更新日期:2020-06-01
down
wechat
bug