Abstract Laser confocal tomography faces severe challenges in weak signal detection such as biological tissue imaging and low-reflection interfaces measurement. An ultra-high sensitive optical confocal tomography based on laser frequency-shifted feedback imaging technology is presented, whose theoretical magnification can reach 106 notably without using high-gain detectors. In addition, this achievement possesses the same tomographic resolution as conventional laser confocal tomography without the need for spatial filtering devices. In this work, supported by theories and experiments, the lateral and vertical resolution, optical sensitivity, and system repeatability of LFCT and traditional LCT are investigated and analyzed quantificationally. Finally, comparison on the results of measuring the microfluidic device and biological tissue sections is conducted.

中文翻译：

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基于频移反馈技术的高灵敏度激光共焦断层扫描

摘要 激光共聚焦断层扫描在生物组织成像和低反射界面测量等弱信号检测方面面临严峻挑战。提出了一种基于激光频移反馈成像技术的超高灵敏度光学共焦层析成像技术，其理论放大倍数可在不使用高增益探测器的情况下显着达到106倍。此外，该成果具有与传统激光共焦断层扫描相同的断层分辨率，无需空间滤波设备。本文在理论和实验的支持下，对LFCT和传统LCT的横向和纵向分辨率、光学灵敏度和系统重复性进行了定量研究和分析。最后，