Excessive daytime sleepiness (EDS) is common in patients with obstructive sleep apnea (OSA) and continues to persist in many patients despite adequate OSA treatment. EDS in OSA is associated with decreased quality of life (QOL) as well as increased societal burden, which may impact health care utilization and costs. However, economic burden is often not the primary focus in the treatment of EDS in OSA. This targeted literature review aimed to examine the published literature on the economic burden of EDS in OSA. This review identified available literature using a targeted PubMed search strategy using search terms related to EDS in OSA in adults. Results demonstrate that there are few studies that detailed the direct costs associated with EDS in OSA, though several studies indicated an association between EDS in OSA and indirect economic burdens, including motor vehicle accidents (MVAs), near misses, work productivity, mood, and QOL. Data from the literature confirmed that persistent EDS in OSA following continuous positive airway pressure persists in 12%–65% of patients. Future studies should further describe the direct costs of EDS in OSA, quantify the cost associated with MVAs and lost work productivity, and detail QOL and social impacts of the condition.

阻塞性睡眠呼吸暂停（OSA）患者常见白天过度嗜睡（EDS），尽管OSA治疗充分，许多患者仍持续这种情况。OSA中的EDS与生活质量（QOL）下降以及社会负担增加有关，这可能会影响医疗保健的利用和成本。但是，经济负担通常不是OSA中EDS治疗的主要重点。这项有针对性的文献综述旨在研究有关OSA中EDS的经济负担的已发表文献。该评价使用针对性的PubMed搜索策略，使用成人OSA中与EDS相关的搜索词，确定了可用文献。结果表明，很少有研究详细说明OSA中与EDS相关的直接成本，尽管几项研究表明OSA中的EDS与间接经济负担之间存在关联，包括机动车事故（MVA），未命中，工作效率，情绪和生活质量。文献数据证实，持续气道正压通气持续存在于OSA中的EDS持续存在于12％–65％的患者中。未来的研究应进一步描述OSA中EDS的直接成本，量化与MVA和丧失的工作效率相关的成本，并详细说明疾病的生活质量和社会影响。