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Playing Favorites: Integrin αvβ5 Mediates Preferential Zika Infection of Neural Stem Cells.
Cell Stem Cell ( IF 23.9 ) Pub Date : 2020-02-06 , DOI: 10.1016/j.stem.2020.01.007
Christine Vazquez 1 , Kellie Ann Jurado 1
Affiliation  

The molecular basis dictating specificity of Zika virus infection in neural stem cells (NSCs) remains elusive. Two recent papers in Cell Stem Cell (Zhu et al., 2020) and Cell Reports (Wang et al., 2020) identify integrin αvβ5 as an internalization factor that increases susceptibility in NSCs and glioblastoma stem cells.

中文翻译:

最喜欢的游戏:整合素αvβ5介导神经干细胞的Zika优先感染。

指示寨卡病毒感染在神经干细胞(NSCs)中的特异性的分子基础仍然难以捉摸。《细胞干细胞》(Zhu等人,2020)和《细胞报告》(Wang等人,2020)上的两篇最新论文将整联蛋白αvβ5鉴定为一种内在因子,可增加NSC和胶质母细胞瘤干细胞的易感性。
更新日期:2020-02-20
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