Human induced pluripotent stem cells (hiPSCs) provide a potentially unlimited cell source for producing autologous tissue-engineered vascular grafts (TEVGs), which currently suffer from low mechanical strength. In this issue of Cell Stem Cell, Luo et al. (2020) describe optimized culture media and a mechanical stretching regimen to produce hiPSC-derived TEVGs with mechanical behavior similar to that of natural vessels.

中文翻译：

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人类iPSC可以改善组织工程化的血管移植物。

人诱导的多能干细胞（hiPSC）为生产自体组织工程化的血管移植物（TEVG）提供了潜在的无限细胞来源，目前这些移植物的机械强度较低。在本期《细胞干细胞》中，Luo等人。（2020）描述了优化的培养基和机械拉伸方案来产生hiPSC衍生的TEVGs，其机械行为类似于天然血管。