A recent paper by Kidokoro et al. (2020) in The Plant Cell reported a transgene‐dependent transcriptional silencing phenomenon in the dominant ice1‐1 Arabidopsis mutant containing the CBF3‐LUC reporter, and questioned whether ICE1 may regulate CBF genes and may be involved in plant cold response. Here, we evaluate available evidence supporting the involvement of ICE1 in plant cold response, and provide ChIP‐seq data showing ICE1 binding to the promoters of CBF genes and other regulatory genes known to be critical for cold response as well as to the promoters of some COR genes.

中文翻译：

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转录因子ICE1通过结合CBF和COR基因的启动子在冷应激反应中发挥作用。

Kidokoro等人的最新论文。（2020）在《植物细胞》中报道了在含有CBF3–LUC报告基因的显性ice1-1拟南芥突变体中转基因依赖性的转录沉默现象，并质疑ICE1是否可能调节CBF基因并可能参与植物的冷反应。在这里，我们评估了支持ICE1参与植物冷响应的现有证据，并提供了ChIP-seq数据，显示ICE1与CBF基因的启动子和已知对寒冷响应至关重要的其他调节基因以及某些启动子的结合COR基因。