Although the utility of double‐stranded RNA (dsRNA)‐mediated knockdown as an environmentally friendly pest management strategy has gained traction in recent years, its overall efficacy has been limited by poor stability and limited cellular uptake. Encapsulation of dsRNAs with various nanomaterials, however, has shown promise in overcoming these limitations. This study sought to investigate the biological efficacy of an oral dsRNA nanomaterial mixture targeting the CYP15C1 gene product in the economically important rice pest, Chilo suppressalis .

中文翻译：

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纳米材料包裹的dsCYP15C1，一种潜在的基于RNAi的害虫防治手掌alis的策略。

尽管近年来双链RNA（dsRNA）介导的基因敲除作为一种环境友好的害虫管理策略的实用性受到了关注，但其整体功效受到稳定性差和细胞摄取受限的限制。然而，用各种纳米材料包裹dsRNA已显示出克服这些局限性的希望。这项研究旨在研究针对CYP15C1基因产物的口服dsRNA纳米材料混合物在经济上重要的水稻害虫Chilo inhibitoralis中的生物学功效。