Reduced risk of ovarian cancer is commonly ascribed to reduced exposure to endogenous hormones during pregnancy, using oral contraceptives or not using hormone replacement therapy. However, exposure to hormones alone account for less than half of all cases. Many women carry small amounts of male cells—known as male origin microchimerism—in their circulation and remarkable impacts of these cells on women’s health are being published. Here, we pursue the possibility that male origin microchimerism has a role in reducing ovarian cancer risk.

中文翻译：

---

男性起源的微嵌合体和卵巢癌

卵巢癌风险的降低通常归因于怀孕期间使用口服避孕药或未使用激素替代疗法减少了对内源性激素的暴露。但是，仅激素的暴露就不足所有病例的一半。许多妇女的血液循环中携带少量男性细胞（称为男性起源的微嵌合体），这些细胞对女性健康的显着影响已被发表。在这里，我们寻找男性起源的微嵌合体在降低卵巢癌风险中起作用的可能性。