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Rendezvous of Retro-2 at the ER.
Nature Chemical Biology ( IF 14.8 ) Pub Date : 2020-03-01 , DOI: 10.1038/s41589-020-0475-3
Hesso Farhan 1
Affiliation  

Retro-2 is a drug that protects cells against bacterial and plant toxins by arresting their trafficking in endosomes. New data show that the target for Retro-2 is surprisingly not within the endosomal system, but on the endoplasmic reticulum.

中文翻译:

ER的Retro-2交会点。

Retro-2是一种通过阻止细胞在核内体中的运输来保护细胞免受细菌和植物毒素侵害的药物。新数据表明,Retro-2的靶点意外不在内体系统内,而是在内质网上。
更新日期:2020-02-17
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