BACKGROUND Endourological procedures are widely used to treat benign urinary disorders and the double-J stent is routinely used. However, its potential impact on sexual function remains unclear. Therefore, we performed a quantitative systematic review to determine the relationship between endourological procedures with or without double-J stent and post-operative sexual function. METHODS We conducted a search of PubMed, EMBASE, Web of Science, and Cochrane Library databases up to December 2018 for studies that compared sexual function before and after endourological procedures. The quality of the included studies was evaluated using the Risk Of Bias In Non-randomized Studies of Interventions (ROBINS-I). We performed subgroup analyses to explore heterogeneity. A random effects model was used to combine the results. RESULTS Five prospective studies involving 485 sexually active participants were identified. Pooled results showed that, in patients without a double-J stent, the change in sexual function after endourological procedures was not significant in men (mean difference [MD]: - 0.61, 95% confidence interval [CI]: - 1.43 to 0.22, p = 0.148) or women (MD: 0.53, 95% CI: - 0.52 to 1.57, p = 0.322). However, in patients with indwelling double-J stent, sexual function scores significantly declined after the procedure in both men (MD: -4.25, 95% CI: - 6.20 to - 2.30, p < 0.001) and women (MD: -7.17, 95% CI: - 7.88 to - 6.47, p < 0.001). CONCLUSIONS Our meta-analysis suggests that indwelling double-J stent after endourological procedures could be a crucial factor causing temporary sexual dysfunction post-operatively. Our results may be used to provide evidence-based advice to patients.

中文翻译：

---

有或没有双J支架的腔内手术对性功能的影响：系统评价和荟萃分析。

背景技术泌尿外科程序被广泛用于治疗良性泌尿系统疾病，并且常规使用双J支架。但是，其对性功能的潜在影响尚不清楚。因此，我们进行了定量的系统评价，以确定有或没有双J支架的内科程序与术后性功能之间的关系。方法我们对截至2018年12月的PubMed，EMBASE，Web of Science和Cochrane图书馆数据库进行了搜索，以比较比较在进行腔内手术之前和之后的性功能的研究。使用非随机干预研究中的偏倚风险（ROBINS-I）评估纳入研究的质量。我们进行了亚组分析以探索异质性。使用随机效应模型来合并结果。结果确定了五项涉及485名性活跃参与者的前瞻性研究。汇总结果显示，在没有双J支架的患者中，男性进行呼吸内科手术后的性功能变化不明显（平均差异[MD]：-0.61，95％置信区间[CI]：-1.43至0.22， p = 0.148）或女性（MD：0.53，95％CI：-0.52至1.57，p = 0.322）。但是，在留有双J支架的患者中，男性（MD：-4.25，95％CI：-6.20至-2.30，p <0.001）和女性（MD：-7.17， 95％CI：-7.88至-6.47，p <0.001）。结论我们的荟萃分析表明，在进行了腔内手术后留置双J支架可能是导致术后暂时性功能障碍的关键因素。