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Validation of rapid magnetic resonance myelin imaging in multiple sclerosis
Annals of Neurology ( IF 11.2 ) Pub Date : 2020-03-02 , DOI: 10.1002/ana.25705
Russell Ouellette 1, 2, 3, 4 , Gabriel Mangeat 3, 5 , Ildiko Polyak 6 , Marcel Warntjes 7, 8 , Yngve Forslin 1, 2 , Åsa Bergendal 1, 9 , Michael Plattén 1, 2, 10 , Martin Uppman 1, 2 , Constantina Andrada Treaba 3, 4 , Julien Cohen-Adad 5 , Fredrik Piehl 1, 11 , Maria Kristoffersen Wiberg 1, 2 , Sten Fredrikson 1, 11 , Caterina Mainero 3, 4 , Tobias Granberg 1, 2, 3, 4
Affiliation  

Magnetic resonance imaging (MRI) is essential for multiple sclerosis diagnostics but is conventionally not specific to demyelination. Myelin imaging is often hampered by long scanning times, complex postprocessing, or lack of clinical approval. This study aimed to assess the specificity, robustness, and clinical value of Rapid Estimation of Myelin for Diagnostic Imaging, a new myelin imaging technique based on time‐efficient simultaneous T1/T2 relaxometry and proton density mapping in multiple sclerosis.

中文翻译:

多发性硬化中快速磁共振髓鞘成像的验证

磁共振成像 (MRI) 对多发性硬化症的诊断至关重要,但通常不适用于脱髓鞘。髓鞘成像通常受到扫描时间长、后处理复杂或缺乏临床批准的阻碍。本研究旨在评估髓鞘快速估计用于诊断成像的特异性、稳健性和临床价值,这是一种新的髓鞘成像技术,基于多发性硬化症的时间效率同步 T1/T2 弛豫测量和质子密度映射。
更新日期:2020-03-02
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