The beet armyworm, Spodoptera exigua , is a serious agricultural pest that is primarily controlled using chemical insecticides. Recently, resistance to the insecticide spinosad has been described in S. exigua field populations. To date, there has been no functional evidence proving the involvement of the nicotinic acetylcholine receptor (nAChR) α6 mutation in spinosad resistance in S. exigua .

中文翻译：

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利用CRISPR / Cas9系统验证烟蛾（Spodoptera exigua）中多杀菌素的靶点烟碱乙酰胆碱受体（nAChR）α6的功能验证。

甜菜夜蛾Spodoptera exigua是一种严重的农业害虫，主要使用化学杀虫剂进行防治。近来，已在S. exigua田间种群中描述了对杀虫剂多杀菌素的抗性。到目前为止，还没有证据的功能证明烟碱型乙酰胆碱受体（胆碱受体）突变α6在多杀菌素阻力在参与甜菜夜蛾。