当前位置: X-MOL 学术N. Engl. J. Med. › 论文详情
ANCA-Associated Vasculitis — Refining Therapy with Plasma Exchange and Glucocorticoids
The New England Journal of Medicine ( IF 70.670 ) Pub Date : 2020-02-13 , DOI: 10.1056/nejme1917490
Vimal K. Derebail; Ronald J. Falk

This article has no abstract; the first 100 words appear below. Plasma exchange has been a mainstay of induction therapy for patients with antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis who have rapidly progressive glomerulonephritis or diffuse alveolar hemorrhage.1-3 Clinical data, in vitro data, and data from studies in animals have shown that ANCAs are pathogenic.4 Plasma exchange rapidly depletes pathogenic ANCAs and theoretically should diminish vascular injury and end-organ damage and hasten resolution of disease. In this issue of the Journal, Walsh et al. report the results of the PEXIVAS trial, a very large randomized clinical trial involving patients with ANCA-associated vasculitis (704 patients with a median follow-up of 2.9 years).5 The . . .
更新日期:2020-02-13

 

全部期刊列表>>
Springer Nature 2019高下载量文章和章节
化学/材料学中国作者研究精选
《科学报告》最新环境科学研究
ACS材料视界
自然科研论文编辑服务
中南大学国家杰青杨华明
剑桥大学-
中南大学
材料化学和生物传感方向博士后招聘
课题组网站
X-MOL
北京大学分子工程苏南研究院
华东师范大学分子机器及功能材料
中山大学化学工程与技术学院
试剂库存
天合科研
down
wechat
bug