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Zieve’s Syndrome: an Unusual Cause of Anemia
SN Comprehensive Clinical Medicine Pub Date : 2020-02-13 , DOI: 10.1007/s42399-020-00236-w Patrick A. Twohig , Aakash Desai , Dalbir S. Sandhu
SN Comprehensive Clinical Medicine Pub Date : 2020-02-13 , DOI: 10.1007/s42399-020-00236-w Patrick A. Twohig , Aakash Desai , Dalbir S. Sandhu
Zieve’s syndrome (ZS) is a rare condition that includes alcoholic hepatitis, hyperlipidemia, and hemolytic anemia. We describe a severe case of ZS in a 39-year-old female patient with refractory symptoms who ultimately succumbed to her liver injury 6 weeks from her initial presentation to the hospital despite multiple attempts at alcohol cessation rehabilitation. Clinicians need to maintain a high index of suspicion for ZS in patients with alcoholic hepatitis who have transfusion refractory anemia. Alcohol abstinence is essential for recovery. The major challenge with this syndrome remains early diagnosis, and our goal is that increased case reporting will raise clinician awareness.
中文翻译:
Zieve综合征:贫血的一种罕见原因
Zieve综合征(ZS)是一种罕见疾病,包括酒精性肝炎,高脂血症和溶血性贫血。我们描述了一名39岁女性患者的ZS严重病例,该患者患有难治性症状,尽管多次尝试戒酒康复,但从她初次到医院后6周最终因肝损伤而屈服。对于患有输血难治性贫血的酒精性肝炎患者,临床医生需要对ZS保持高度怀疑。戒酒对于康复至关重要。该综合征的主要挑战仍然是早期诊断,我们的目标是增加病例报告将提高临床医生的认识。
更新日期:2020-02-13
中文翻译:
Zieve综合征:贫血的一种罕见原因
Zieve综合征(ZS)是一种罕见疾病,包括酒精性肝炎,高脂血症和溶血性贫血。我们描述了一名39岁女性患者的ZS严重病例,该患者患有难治性症状,尽管多次尝试戒酒康复,但从她初次到医院后6周最终因肝损伤而屈服。对于患有输血难治性贫血的酒精性肝炎患者,临床医生需要对ZS保持高度怀疑。戒酒对于康复至关重要。该综合征的主要挑战仍然是早期诊断,我们的目标是增加病例报告将提高临床医生的认识。