We have read with great interest the study by Huitema et al. [1] showing a pulmonary hypertension (PH) prevalence of around 3% in a large cohort of predominantly Caucasian sarcoidosis patients in a Dutch tertiary centre. According to the authors, a European Caucasian cohort has never been studied before this PULmonary hypertension in pulmonary SARcoidosis (PULSAR) study. In this context, in 2013 we reported another PULSAR study (PULmonary hypertension in SARcoidosis) in an albeit smaller cohort from a German tertiary centre [2]. Of interest, we showed very similar results, with a prevalence of precapillary PH of 3.6% with a similar study design in Caucasian sarcoidosis patients. A cumulative analysis of both PULSAR trials would demonstrate sarcoidosis-associated pulmonary hypertension proven by right heart catheter in 15/510 patients and precapillary PH in 13/510 patients http://bit.ly/34VGWbv

中文翻译：

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结节病相关肺动脉高压的患病率：两项 PULSAR 研究的累积分析

我们非常感兴趣地阅读了 Huitema 等人的研究。[1] 荷兰三级中心的一大群主要是白种人结节病患者的肺动脉高压 (PH) 患病率约为 3%。这组作者说，在肺 SARcoidosis (PULSAR) 研究之前，从未对欧洲白种人队列进行过研究。在这种情况下，我们在 2013 年报告了另一项 PULSAR 研究（SARcoidosis 中的 PULmonary 高血压），尽管来自德国三级中心的队列规模较小 [2]。有趣的是，我们显示了非常相似的结果，在白种人结节病患者中采用类似的研究设计，毛细血管前 PH 的患病率为 3.6%。