OBJECTIVE Cutaneous adverse events (CAE) from FreeStyle Libre include allergic contact dermatitis (ACD) caused by the allergen isobornyl acrylate (IBOA). We aim to report CAE from this glucose sensor, ACD to IBOA in particular, and the outcome of using barrier films as a prevention. RESEARCH DESIGN AND METHODS A monocentric, retrospective review of medical files from adult and pediatric patients with diabetes using Freestyle Libre, in the period between December 2016 and April 2019, was performed with a focus on CAE. RESULTS Fifty-seven of 1,036 patients with diabetes (5.5%) were referred to our Dermatology department because of CAE from FreeStyle Libre. Thirty-nine of 1,036 (3.8%) had ACD due to IBOA. Only two patients, of whom one sensitized to IBOA, had a benefit from using barrier films. CONCLUSIONS CAE occurred in 5.5% of FreeStyle Libre users, and 3.8% suffered from ACD due to IBOA. Barrier films had a limited value in the prevention.

中文翻译：

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FreeStyle Libre引起的接触性皮炎的患病率和预防：单中心体验。

目的FreeStyle Libre的皮肤不良事件（CAE）包括由过敏原丙烯酸异冰片酯（IBOA）引起的过敏性接触性皮炎（ACD）。我们旨在报告这种葡萄糖传感器产生的CAE，尤其是ACD到IBOA，以及使用屏障膜作为预防措施的结果。研究设计和方法在2016年12月至2019年4月期间，使用Freestyle Libre对成年和小儿糖尿病患者的医疗档案进行了单中心回顾性研究，重点是CAE。结果1,036名糖尿病患者中有57名（5.5％）因FreeStyle Libre的CAE转诊至我们的皮肤科。1,036名患者中有39名（3.8％）因IBOA而患有ACD。只有两名患者对IBOA过敏，使用隔离膜可以使患者受益。结论CAE发生于5岁。FreeStyle Libre用户中有5％的人因IBOA而遭受ACD的困扰，而有3.8％的人患有ACD。隔离膜在预防中的价值有限。